The following are the areas of research in the department

Thrust areas

  1. Metabolic bone diseases including osteoporosis

    1. Prevalence of osteoporosis and Vitamin D deficiency in postmenopausal women in Vellore

    2. Vitamin D deficinecy and bone mineral density in HIV infected patients on anti retroviral therapy

    3. Risk factors for femoral neck fracture in Indian women and BMD threshold for femoral neck fracture in Indian women

    4. Prevalence of Vitamin D deficiency in school children in Vellore

    5. Efficacy of Vitamin D supplementation on enhancing BMD in children with minimal lesion glomerulonephritis on corticosteroid therapy

    6. Efficacy of IV Zoledronic acid in preventing bone loss in quadriplegics

    7. Clinical trials on SERMs, Cathepsin K inhibitors and monoclonal antibodies in postmenopausal osteoporosis

    8. Fluorosis and its impact on bone and kidney

    9. Pancreatic osteodystrophy in patients with fibrocalcific pancreatitis and diabetes mellitus

    10. Vitamin D status in patients with Crohn's disease

    11. Body composition analysis in HIV positive individuals with or without antiretroviral therapy

    12. Paget's disease of bone : Intervention, follow-up and outcomes

    13. Filter-paper method for determination of HbA1C to facilitate access of this important test to Diabetic patients residing in remote areas

Pituitary disorders

  1. Hydrocortisone use in postoperative diabetes insipidus and its relation to postoperative diabetes insipidus

  2. Long term Follow-up of patients with functioning and clinically non-functioning pituitary tumors with a view to evolving new therapeutic strategies

  3. Assessing aggressiveness of pituitary tumors by evaluating apoptosis and anti apoptosis markers in tissue sections by immunohistochemistry

  4. Pituitary apoplexy Risk factors

Multiple Endocrine Neoplasia

  1. Establishing a method for genetic screening for first degree relatives of patients with MEN I, MEN IIA and MEN IIB syndromes

  2. Establishing a method for discriminating between benign and malignant thyroid nodules based on evaluation of microRNA on FNAC specimens

Menopausal disorders
  1. Management strategies for menopausal symptoms based on non-hormonal agents